Current status of aggressive blood pressure control

Table 2 Clinical trials without clear evidence of J-curve effect

Author	Subjects	Age (yr)	Follow-up (yr)	Baseline (DBP mmHg)	CAD (present)	J-curve effect MI	Stroke	DBP (mmHg)
Wilhelmsen et al[26]	6569	40-60	3.9	107	Yes	Yes2	No	88-89
Coope et al[27]	884	60-79	4.4	98	Yes	Yes1	No	80-89
Lubsen et al[29]	7661	63.0	4.9	85	Yes	Yes3	No	85
Psaty et al[30]	4702	72.6	6.7	71	No	No	No	62
Glynn/PHS[31]	22 071	53.2	13.0	79	Yes	No	No	65
Glynn/WHS[31]	39 876	53.8	6.2	78	No	No	No	70

¹Present in female smokers;

²Present for trend;

³Present for trend. CAD: Coronary artery disease; DBP: Diastolic blood pressure; MI: Myocardial infarction.