Risk profile and outcomes of aortic valve replacement in octogenarians

Table 2 Perioperative and postoperative outcomes n (%)

	All patients (n = 273)	LES < 15 (n = 193)	LES≥15 (n = 80)	Effect (95% CI)	P value
Stroke	13 (5)	8 (4)	5 (6)	OR 1.54 (0.49-4.86)	0.460
MI	3 (1)	3 (2)	0
Cardiac tamponade	14 (5)	7 (4)	7 (9)	OR 2.55 (0.86.7.52)	0.090
Gastrointestinal bleeding	11 (4)	8 (4)	3 (4)	OR 0.90 (0.23-3.49)	0.880
Infection	22 (8)	15 (8)	7 (9)	OR 1.14 (0.45-2.91)	0.790
Renal impairment	44 (16)	26 (14)	18 (23)	OR 1.86 (0.96-3.64)	0.070
PPM insertion	23 (8)	14 (7)	9 (11)	OR 1.60 (0.66-3.87)	0.290
Mortality
30 d	19 (7)	8 (4)	11 (14)	OR 3.69 (1.42-9.55)	0.007
≤ 90 d	31 (11)	16 (8)	15 (19)	OR 2.55 (1.19-5.46)
> 90 d	22 (8)	10 (5)	12 (15)		0.020
Discharge
Home	153 (56)	118 (61)	35 (44)
Other hospital or Ward	97 (36)	64 (33)	33 (41)
Survival (yr), median (IQR)	6.22 (3.00-10.94)	8.74 (3.54-11.07)	4.19 (1.83-5.94)	HR 2.12 (1.40-3.22 )	< 0.001
1 yr postop (95% CI)	87% (82%-90%)	90% (85%-94%)	79% (68%-86%)
5 yr postop (95% CI)	57% (49%-64%)	64% (54%-72%)	40% (26%-55%)
ICU stay
Median (IQR)	1 (1-3)	1 (1-3)	2 (1-3)	HR 0.86 (0.66-1.14)	0.290
Death pre ICU	6 (2)	2 (1)	4 (5)
HDU stay
Median (IQR)	3 (1-4)	2 (1-4)	4 (2-5)	HR 0.67 (0.50-0.89)	0.006
Death pre HDU	13 (5)	5 (3)	8 (10)
Ward stay
Median (IQR)	6 (4-9)	6 (4-9)	5 (4-8)	HR 1.16 (0.87-1.55)	0.310
Death pre ICU	17 (6)	7 (4)	10 (13)
Overall, median (IQR)	11 (8-15)	11 (8-15)	11 (8-15)	HR 0.89 (0.67-1.17)	0.400

Effect sizes and P values are for comparisons between the Logistic EuroSCORE (LES) < 15 and LES ≥ 15 groups. Missing data: Discharge destination - low risk (n = 1); Pacemaker insertion - low risk (n = 2); high dependency unit (HDU) and ward length of stay - low risk (n = 2). ICU: Intensive care unit; OR: Odds ratio; HR: Hazard ratio; PPM: Permanent pacemaker; IQR: Interquartile range.