Epicardial coronary artery intimal smooth muscle hyperplasia in a cocaine user

Figure 1 Sections at different segments of the proximal left anterior descending coronary artery. A: Hematoxylin and eosin stain; B: Smooth muscle actin immunohistochemistry (Original magnification, 40 ×). Note intimal expansion and critical luminal compromise in both sections; B shows that most of the intimal expansion is due to smooth muscle cells.