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World J Cardiol. Oct 26, 2011; 3(10): 329-336
Published online Oct 26, 2011. doi: 10.4330/wjc.v3.i10.329
Published online Oct 26, 2011. doi: 10.4330/wjc.v3.i10.329
Table 1 Distribution of genotypes and allelic frequencies of ACE and bradykinin B2 receptor polymorphisms in patients with or without cough
| Population | Studies | Genotype | χ2test | Studies | Allele | Odds ratio(95% CI) | |||||
| I/I | I/D | D/D | I | D | |||||||
| Angiotensin converting enzyme | All | 11 | Cough (-) | 390 (32) | 571 (48) | 241 (20) | 0.004 | 7 | 0.51 | 0.49 | 1.26 (0.99-1.61) |
| Cough (+) | 338 (39) | 381 (44) | 142 (17) | 0.45 | 0.55 | ||||||
| Caucasians | 3 | Cough (-) | 75 (24) | 132 (43) | 100 (33) | 0.230 | 2 | 0.53 | 0.47 | 0.72 (0.46-61.4) | |
| Cough (+) | 23 (19) | 51 (41) | 50 (40) | 0.61 | 0.39 | ||||||
| East Asians | 8 | Cough (-) | 315 (35) | 439 (49) | 141 (16) | 0.005 | 5 | 0.49 | 0.51 | 1.49 (1.11-12.02) | |
| Cough (+) | 315 (43) | 330 (45) | 92 (12) | 0.39 | 0.61 | ||||||
| T/T | T/C | C/C | C | T | |||||||
| B2 receptor B2 receptor -58T/C | East Asians | 3 | Cough (-) | 145 (26) | 270 (50) | 143 (24) | 0.015 | 2 | 0.56 | 0.44 | 2.25 (1.42-23.57) |
| Cough (+) | 139 (30) | 244 (52) | 85 (18) | 0.36 | 0.64 | ||||||
- Citation: Nishio K, Kashiki S, Tachibana H, Kobayashi Y. Angiotensin-converting enzyme and bradykinin gene polymorphisms and cough: A meta-analysis. World J Cardiol 2011; 3(10): 329-336
- URL: https://www.wjgnet.com/1949-8462/full/v3/i10/329.htm
- DOI: https://dx.doi.org/10.4330/wjc.v3.i10.329