Central obesity, hypertension and coronary artery disease: The seed and soil hypothesis

Figure 1 Pedigree chart corroborating the “seed and soil“ hypothesis. Effect of environmental factors such as smoking on the eldest child, physical inactivity manifesting as central obesity in all due to a sedentary lifestyle in the second generation culminating in various sequelae of metabolic syndrome and prehypertension evolving into hypertension in the third generation. BMI: Body mass index; BP: Blood pressure; CAD: Coronary artery disease; CAG: Coronary angiography; CART: Coronary arteriography; CIMT: Carotid intima media thickness; DM: Diabetes mellitus; Dyslip: Dyslipidemia; HTN: Hypertension; Lp(a): Lipoprotein (a); TVD: Triple vessel disease; WHR: Waist hip ratio.