Atrial fibrillation and inflammation

Table 2 Polyunsaturated fatty acids and atrial fibrillation

Ref.	Study design	Subjects	Conclusion
Physicians’ Health Study[54]	Prospective	17 679 patients (epidemiological study)	Although statistically insignificant, AF risk is higher in PUFAs group
Danish study[53]	Prospective	47 949 patients (epidemiological study)	Although statistically insignificant, AF risk is higher in PUFAs group
Rotterdam study[55]	Prospective	5184 patients (epidemiological study)	Although statistically insignificant, AF risk is higher in PUFAs group
Mozaffarian et al[51]	Prospective	4815 patients (epidemiological study)	Although statistically insignificant, AF risk is higher in fried fish/fish sandwich group
			Significantly, AF risk is lower in broiled/baked fish group
Calò et al[48]	Prospective	160 patients undergoing CABG surgery	AF risk is significantly lower in PUFAs group
Saravanan et al[49]	Prospective	Patients undergoing CABG surgery	AF risk is significantly lower in PUFAs group

PUFAs: Polyunsaturated fatty acids; AF: Atrial fibrillation; CABG: Coronary artery bypass grafting.