Impaired diastolic function in naïve untreated human immunodeficiency virus infected patients

Table 4 Diastolic function in HIV patients and control subjects (mean ± SD)

	HIV patients(n = 53)	Control subjects (n = 56)	P
Transmitralic Doppler
Peak E wave velocity (cm/s)	62.7 ± 18.3	79.1 ± 16.4	< 0.001
Peak A wave velocity (cm/s)	57.8 ± 15.7	65.5 ± 21.1	< 0.050
E/A ratio	1.11 ± 0.26	1.25 ± 0.20	< 0.001
Dct (ms)	190.7 ± 24.8	178.1 ± 26.5	< 0.050
IVRT (ms)	98.1 ± 14.3	86.9 ± 14.4	< 0.010
Tissue Doppler
Peak Em wave velocity (cm/s)	12.7 ± 8.2	18.9 ± 5.6	< 0.001
Peak Am wave velocity (cm/s)	10.0 ± 6.9	14.3 ± 4.9	< 0.001
Em/Am ratio	1.18 ± 0.36	1.36 ± 0.24	< 0.010
Combined index
E/Em ratio	6.6 ± 3.5	4.5 ± 1.9	< 0.001

Dct: E wave deceleration time (ms); IVRT: Isovolumetric relaxation time (ms).