Percutaneous coronary intervention for unprotected left main coronary artery stenosis

Table 3 Comparison of drug-eluting stents to coronary artery bypass surgery for unprotected left main coronary artery stenosis

	Chieffo et al[7]		Lee et al[9]		Palmerini et al[15]		Buszman et al[17]		Seung et al[21]
Study design	Registry		Registry		Registry		Randomized study		Registry
Treatment type	PCI with SES, PES	CABG	PCI with SES	CABG	PCI with SES	CABG	PCI with BMS, DES	CABG	PCI with BMS, DES	CABG
No. of patient	107	142	50	123	157	154	52	53	1102	1138
Age (yr)	64	68	72	70	73a	69	61	61	62	64
Ejection fraction (%)	52	52	51	52	52	55	54	54	62	60
EuroSCORE or Parsonnet score (Lee)	4.4	4.3	18.0a	13.0	6.0a	5.0	3.3	3.5	NA	NA
Initial clinical outcomes	In-hospital		30 d		30 d		30 d		NA
Death (%)	0.0	2.0	2.0	5.0	3.2	4.5	0.0	0.0	NA	NA
Myocardial infarction (%)	9.0	26.0	0.0	2.0	4.5	1.9	1.9	3.8	NA	NA
TVR (%)	0.0	2.0	0.0	1.0	0.6	0.6	1.9	0.0	NA	NA
Any MACE (%)	NA	NA	0.0	8.0	NA	NA	NA	NA	NA	NA
Cerebrovascular accident	0.0	1.4	2.0a	17.0	NA	NA	0.0	2.0	NA	NA
Long-term clinical outcomes	Cumulative after discharge		Kaplan-Meier		Cumulative		At 1 yr		Kaplan-Meier at 3 yr for propensity-matched cohort
Mean follow-up (mo)	12.0	12.0	6.0	6.0	14.0	14.0	NA	NA	33.9	38.4
Death (%)	2.8	6.4	4.0	13.0	13.4	12.3	1.9	7.5	7.9	7.8
Myocardial infarction (%)	0.9	1.4	NA	NA	8.3	4.5	1.9	5.7	NA	NA
TVR (%)	19.6a	3.6	7.0	1.0	25.5a	2.6	28.8a	9.4	12.6	2.6
Cerebrovascular accident (%)	0.9	0.7	NA	NA	NA	NA	0.0	3.8	NA	NA
Any events (%)	NA	NA	11.0	17.0	NA	NA	NA	NA	NA	NA

^aP < 0.05 between PCI vs CABG.