Percutaneous coronary intervention for unprotected left main coronary artery stenosis

doi:10.4330/wjc.v2.i4.78

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Cardiol. Apr 26, 2010; 2(4): 78-88
Published online Apr 26, 2010. doi: 10.4330/wjc.v2.i4.78

Table 1 Outcomes of drug-eluting stents for unprotected left main coronary artery stenosis

	*Chieffo et al[4]*		*Valgimigli et al[6]*		*Park et al[5]*		*de Lezo et al[28]*	*Price et al[11]*	*Kim et al[20]*	*Meliga et al[29]*	*Mehilli et al[48]*
Stent type	SES, PES	BMS	SES, PES	BMS	SES	BMS	SES	SES	SES, PES	SES, PES	PES	SES
Design	Single center study		Single center study		Single center study		Single center study	Single center study	Single center study	Multicenter DELFT study	Multicenter randomized study
No. of patient	85	64	95	86	102	121	52	50	63	358	302	305
Age (yr)	63	66	64	66	60	58	63	69	67	66	69	69
Ejection fraction (%)	51^a	57	41	42	60	62	57	NA	50	49	53	54
Acute myocardial infarction (%)	NA	NA	17	20^a	9.8	6.6	NA	NA	5	8.4	NA	NA
Bifurcation involvement (%)	81^a	58	65	66	71^a	43	42	94	54	74	63	63
Two-stent technique (%)	74	NA	40^a	15	41^a	18	18	89	17	43	51	49
Initial clinical outcomes	In-hospital		30 d		In-hospital		In-hospital	In-hospital	In-hospital	In-hospital	30 d
Death (%)	0	0	11	7	0	0	0	0	0	3	1	2
Myocardial infarction (%)	6	8	4	9	7	8	4	8	10	7	4	4
Stent thrombosis (%)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	4.0	0.0	NA	0.3	0.7
TVR (%)	0.0	2.0	0.0	2.0	0.0	0.0	0.0	6.0	0.0	0.8	0.3 (TLR)	0.7 (TLR)
Any events, %	NA	NA	15.0	19.0	7.0	8.0	4.0	10.0	10.0	11.0	5.0	4.6
Long-term outcomes (%)	Cumulative		Cumulative		Cumulative		Cumulative	After discharge	Cumulative	3 yr	2 yr
Mean follow-up (mo)	6	6	17	12	12	12	12	9	11	NA	NA	NA
Death (%)	4	14	14	16	0	0	0	10	5	9	10	9
Myocardial infarction (%)	NA	NA	4^a	12	7	8	4	2	11	9	5	5
Stent thrombosis (%)	0.1	0.0	NA	NA	0.0	0.0	0.0	0.0	0.2	0.6	0.3	0.7
TVR (%)	19	31	6^a	12	2^a	17	2	38	19	14	9 (TLR)	11 (TLR)
Any MACE (%)	NA	NA	24^a	45	8^a	26	NA	44	29	32	21	21

^aP < 0.05 between drug-eluting stent (SES and/or PES) vs BMS. BMS: Bare metal stent; NA: Not available; MACE: Major adverse cardiac events including death, myocardial infarction, and TVR; PES: Paclitaxel-eluting stent; SES: Sirolimus-eluting stent; TVR: Target vessel revascularization; DELFT: Drug Eluting stent for left main.

Citation: Park SJ, Kim YH. Percutaneous coronary intervention for unprotected left main coronary artery stenosis. World J Cardiol 2010; 2(4): 78-88
URL: https://www.wjgnet.com/1949-8462/full/v2/i4/78.htm
DOI: https://dx.doi.org/10.4330/wjc.v2.i4.78