Renal impairment and heart failure with preserved ejection fraction early post-myocardial infarction

Table 2 Multivariable correlates of heart failure

Covariates	P value	OR	95% CI
All patients (n = 2096)
Decreasing EF1	< 0.0001	1.554	1.398-1.727
Increasing BMI	0.001	1.037	1.015-1.059
Decreasing eGFR1	0.006	1.088	1.025-1.156
Increasing age1	0.007	1.171	1.044-1.315
Increasing heart rate1	0.001	1.183	1.075-1.302
Collaterals not present (Grade 0)	0.045	1.397	1.007-1.939
Patients with preserved EF (n = 1402)
Increasing BMI	0.0001	1.060	1.029-1.093
Decreasing eGFR1	0.003	1.140	1.044-1.245
Prior MI	0.021	1.701	1.082-2.673
Increasing age1	0.031	1.185	1.015-1.383
Increasing heart rate1	0.030	1.161	1.014-1.328
Patients with depressed EF (n = 715)
Decreasing EF1	< 0.0001	2.096	1.633-2.689
Decreasing eGFR1	0.181	1.056	0.975-1.143
Increasing heart rate1	0.006	1.210	1.055-1.388
Collaterals not present (Grade 0)	0.036	1.632	1.032-2.581

¹Odds ratios (ORs) and confidence intervals (CIs) reported for a 10 unit change. The addition of an EF*eGFR interaction term did not contribute significantly to the model for all patients, when EF within the interaction term was entered as a continuous variable (P = 0.575) or as a dichotomous variable, i.e. preserved vs depressed (P = 0.151).