Intravascular ULTRA sound-guided percutaneous coronary intervention in patients with STEMI: Rationale and design of the ULTRA-STEMI trial

Table 2 Variables collected and assessed in each patient enrolled in the ULTRA-STEMI trial

Data	Pre-intervention	Post-intervention	Post-optimization
IVUS data	Vessel, lumen and plaque cross-sectional area; Minimal lumen area; Plaque area and burden; Calcium severity; Supposed thrombus presence; Thrombus morphology (acute, subacute, organized)	Stent expansion; Plaque burden at stent edges; Edge dissection; Haematoma; Malapposition; Thrombus protrusion through stent struts; Percentage area stenosis	Minimum stent area; Stent underexpansion; Stent malapposition; Stent deformation; Stent edge dissection; Residual disease at stent edge
	Pre-PCI	Post-PCI
Echocardiographic data	LVEF	LVEF
Clinical data	Medical history; electrocardiographic and laboratory data; IIb/IIIa inhibitors/heparin administration	Electrocardiographic and laboratory data; Stent length and diameter; Amount of contrast drug administered; PCI and CA duration; Total effective radiation dose; Total fluoroscopy time; Number and type of stents; Number of catheters used; ST-segment resolution
Micro-CT data		Thrombus volume
	n.a.	Thrombus density
Angiographic data	Pre-procedural TIMI flow; Thrombus burden classification; Culprit vessel; Number of diseased vessels; SYNTAX score	Angiographically evident residual thrombus burden; Myocardial no-reflow phenomenon; Post-procedural TIMI flow; Distal embolization
Follow-up data	n.a.	Mortality (+cause); CV-hospitalization; MI/revascularization(+vessel); Thromboembolic or bleeding event; Peri- and post-procedural complications

CA: Coronary angiography; CV: Cardiovascular; IVUS: Intravascular ultrasound; LVEF: Left ventricular ejection fraction; MI: Myocardial infarction; Micro-CT: Micro-computed tomography; n.a: Not applicable; PCI: Percutaneous coronary intervention; TIMI: Thrombolysis in myocardial infarction.