Systematic Reviews
Copyright ©The Author(s) 2025.
World J Cardiol. Apr 26, 2025; 17(4): 104168
Published online Apr 26, 2025. doi: 10.4330/wjc.v17.i4.104168
Table 1 Baseline characteristics of included studies
Trial name
Ref.
Year
Location
Total sample
Sample size (TAVR/SAVR)
Mean age (years)
Follow-up (years)
PARTNER 1Smith et al[26]2011United States, Canada, and Germany69934835184 ± 6.61
Kodali et al[27]2012United States, Canada, and Germany69934835184 ± 6.62
Mack et al[28]2015United States, Canada, and Germany69934835184 ± 6.65
Medtronic Core Valve® United States Pivotal TrialAdams et al[7]2014United states74739035783.2 ± 6.71
Reardon et al[8]201575039135983.2 ± 6.72
Deeb et al[9]201675039135983.2 ± 6.73
Arnold et al[10]202171337733683.2 ± 6.75
NOTIONThyregod et al[18]2015Northern Europe28014513579.1 ± 4.81
Søndergaard et al[19]201628014213479.1 ± 4.82
Thyregod et al[20]201928014513579.1 ± 4.85
PARTNER 2Leon et al[11]2016United States, Canada20321011102181.5 ± 6.72
Makkar et al[12]202020321011102181.5 ± 6.75
Medtronic SURTAVI trialReardon et al[14]2017United States166086379479.8 ± 6.22
PARTNER 3Mack et al[15]2019United States950496454731
Leon et al[16]20211,000503497732
Mack et al[17]20231000503497735
Evolut low-riskPopma et al[23]2019Australia, Canada, France, Japan, the Netherlands, New Zealand, and the United States140372567873.9 ± 5.851 and 2
Forrest et al[24]2022Australia, Canada, France, the Netherlands, New Zealand, Japan, and the United States141473068473.9 ± 5.852
Forrest et al[25]2023Australia, Canada, France, the Netherlands, New Zealand, Japan, and the United States141473068473.9 ± 5.853
UK TAVIToff et al[21]2022United Kingdom93145845581 ± 3.71
The VIVA trialRodés-Cabau et al[13]2024United States156797775.5 ± 5.11-5
DEDICATE-DZHK6Blankenberg et al[22]2024Germany141470171374 ± 41
TAVR: Transcatheter aortic valve replacement; SAVR: Surgical aortic valve replacement.