Profiling and bioinformatics analyses of circular RNAs in myocardial ischemia/reperfusion injury model in mice

Figure 2 Circular RNA expression profile comparison between the ischemia/reperfusion group (ischemia/reperfusion 1-3) and sham group (C 1-3). A: Hierarchical clustering demonstrates the differential circular RNA (circRNA) expression profiling between the ischemia/reperfusion group and sham group; B: The number of circRNAs identified in the two groups; C: Volcano plot shows a difference of circRNA expression between the two groups. In the volcano plots, the red and green points represent the circRNAs with log 20-fold changes (up and down regulated) with statistical significance (P < 0.05); D: Box plot shows the distribution of circRNA expression patterns of two group of samples was not different. I/R: Ischemia/reperfusion.