Impact of D-dimer on in-hospital mortality following aortic dissection: A systematic review and meta-analysis

Table 1 Baseline characteristics of included study population, n (%)

Ref.	Year	Country	Study design	Mean age/median age	Male	Total AD cases	Type of AD	Total cases with mortality in AD	Diagnostic technique
Feng et al[15]	2022	China	Prospective cohort	51.86 ± 10.76	396 (87.26)	470	Type A	151	CT angiography
Wang et al[10]	2022	China	Retrospective cohort	54	121 (75.6)	160	Type A	36	Aorta angiography with multidetector CT
Zhang et al[9]	2021	China	Retrospective cohort	52.76 ± 11.73	172 (76.8)	224	Type A	33	CTA, and color doppler echocardiography
Keskin et al[13]	2021	Turkey	Retrospective cross-sectional	61 ± 12	99 (65.6)	151	Type A	35	Contrast-enhanced CTA or MRA
Liu et al[5]	2021	China	Retrospective cohort	52	326 (89.8)	363	Type B	26	Multidetector contrast-enhanced CT
Xie et al[4]	2021	China	Retrospective cohort	Survived: 50.67 ± 11.49, died: 52.47 ± 12.52	279	345	Type A and Type B	75	CT/MRI
Zhang et al[11]	2020	China	Retrospective cohort	50 ± 12	149 (80)	186	Type A	40	CT
Yang et al[7]	2020	China	Retrospective cohort	Training set: 50.10 ± 11.58, validation set: 51.55 ± 10.62	536	703	Type A	235	CTA or MRA
Guo et al[14]	2019	China	Prospective cohort	Survived: 52.0 ± 13.0, died: 52.1 ± 10.2	73	109	Type A and type B	31	Contrast-enhanced CT
Itagaki et al[2]	2018	Japan	Retrospective cohort	64.5	143 (54.58)	262	Type A	23	Contrast-enhanced CT
Li et al[8]	2017	China	Retrospective	51.1 ± 13.1	262 (79.6)	329	Type A	66	CTA
Huang et al[6]	2015	China	Prospective cohort	48.5 ± 11.5	161 (75.9)	212	Type A	27	Multidetector CT
Wen et al[12]	2013	China	Prospective cohort	Survived: 48.9 ± 7.6, died: 48.6 ± 7.6	96	114	Type A and Type B	31	Chest radiography, transthoracic or transesophageal echocardiography and contrast-enhanced CT

AD: Aortic dissection; CT: X-ray micro-computed tomography; CTA: Computed tomography angiography; MRA: Magnetic resonance angiography.