Epicardial adipose tissue in obesity with heart failure with preserved ejection fraction: Cardiovascular magnetic resonance biomarker study

doi:10.4330/wjc.v16.i3.149

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World Journal of Cardiology

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1949-8462

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World J Cardiol. Mar 26, 2024; 16(3): 149-160
Published online Mar 26, 2024. doi: 10.4330/wjc.v16.i3.149

Table 2 Cardiac magnetic resonance parameters of chamber size, function, epicardial adipose tissue volume of the obesity in populations with and without heart failure with preserved ejection fraction

CMR parameters	HFpEF+ (n = 17)	HFpEF- (n = 45)	P value
Conventional parameters
LVEF (%)	0.60 ± 0.03	0.64 ± 0.01	0.0797
LV mass index (g/m²)	61.38 ± 4.55	52.68 ± 1.40	0.0181^a
LVEDD (mm)	52.74 ± 1.80	50.20 ± 0.57	0.0833
LVMWT (mm)	10.32 ± 0.40	9.66 ± 0.25	0.1765
LVEDVi (mL/m²)	74.00 ± 5.52	69.16 ± 1.72	0.2716
LVESVi (mL/m²)	32.12 ± 5.87	24.84 ± 0.78	0.0592
LA AP diameter (mm)	41.37 ± 1.53	42.15 ± 0.87	0.6518
LA LR diameter (mm)	67.85 ± 2.55	70.63 ± 1.18	0.2686
Epicardial adipose tissue
EAT volume (mL)	160.00 ± 7.13	139.80 ± 5.39	0.0449^a
EATi (mL/m²)	74.20 ± 3.16	65.37 ± 2.23	0.0360^a
EAT mass (g)	147.20 ± 6.56	128.60 ± 4.98	0.0451^a
EAT mass index (g/m²)	68.26 ± 2.91	60.10 ± 2.06	0.0359^a
EAT/LA AP diameter ratio	3.56 ± 0.18	3.11 ± 0.14	0.0843
EAT/LA LR diameter ratio	2.19 ± 0.11	1.84 ± 0.08	0.0203^a
EAT/LV mass ratio	1.21 ± 0.09	1.17 ± 0.06	0.7737
EAT/LV volume ratio	0.99 ± 0.08	0.92 ± 0.04	0.4158

^aP < 0.05.

Data were given as means ± standard deviations. AP: Anterior-posterior diameter; CMR: Cardiovascular magnetic resonance; LA: Left atrial; LR: left-right diameter; LVEDVi: Left ventricular end-diastolic volume index; LVEF: Left ventricular ejection fraction; LVESVi: Left ventricular end-systolic volume index; LVMWT: LV maximal wall thickness; LVEDD: Left ventricular end-diastolic diameter; EAT: Epicardial adipose tissue; EATi: Epicardial adipose tissue index.

Citation: Shao JW, Chen BH, Abu-Shaban K, Baiyasi A, Wu LM, Ma J. Epicardial adipose tissue in obesity with heart failure with preserved ejection fraction: Cardiovascular magnetic resonance biomarker study. World J Cardiol 2024; 16(3): 149-160
URL: https://www.wjgnet.com/1949-8462/full/v16/i3/149.htm
DOI: https://dx.doi.org/10.4330/wjc.v16.i3.149