Independent prognostic value of lipocalin-2 in congenital heart disease-associated pulmonary artery hypertension

Table 2 Correlations of mean pulmonary artery pressure, lipocalin-2 and endothelin-1 with clinical variables

Variables	mPAP		LCN2		ET-1
	r	P value	r	P value	r	P value
Sex	0.087	0.475	0.031	0.800	-0.115	0.347
Age in months	0.298	0.013	0.319	0.008	0.048	0.698
BMI	-0.089	0.483	-0.128	0.310	-0.248	0.046
Creatinine in μmol/L	0.389	0.001	0.094	0.446	-0.156	0.205
BUN in mmol/L	0.328	0.006	-0.040	0.747	-0.070	0.568
Albumin in g/L	0.066	0.594	-0.072	0.563	-0.238	0.052
Glucose in mmol/L	-0.174	0.166	0.021	0.869	-0.004	0.973
Hemoglobin in g/L	0.217	0.074	0.080	0.514	-0.173	0.156
Platelets as 109/L	0.007	0.958	-0.128	0.293	-0.098	0.422
White blood cells as 109/L	0.345	0.019	0.291	0.050	0.107	0.480
SBP in mmHg	0.135	0.280	0.074	0.554	0.033	0.795
DBP in mmHg	0.097	0.438	0.106	0.399	0.003	0.983
EF as %	-0.107	0.388	-0.176	0.155	-0.021	0.864
Diameter in mm	0.371	0.002	0.081	0.516	0.230	0.063
mPAP in mmHg	-	-	0.544	< 0.001	0.508	< 0.001
LCN2 in ng/mL	0.544	< 0.001	-	-	0.427	< 0.001
ET1 in μg/mL	0.508	< 0.001	0.427	< 0.001	-	-

BMI: Body mass index; BUN: Blood urea nitrogen; DBP: Diastolic blood pressure; EF: Ejection fraction; ET-1: Endothelin-1; LCN2: Lipocalin-2; mPAP: Mean pulmonary artery pressure; SBP: Systolic blood pressure.