Cardiac hypertrophy in polycythemia vera: A case report and review of literature

Table 5 World Health Organization criteria for polycythemia vera

Major criteria	Minor criterion
Hemoglobin 16.5 g/dL in men Hemoglobin 16.0 g/dL in women, or Hematocrit 49% in men Hematocrit 48% in women, or increased RCM1	Subnormal serum erythropoietin level
BM biopsy showing hypercellularity for age with trilineage growth (panmyelosis) including prominent erythroid, granulocytic, and megakaryocytic proliferation with pleomorphic, mature megakaryocytes (differences in size)
Presence of JAK2 V617F or JAK2 exon 12 mutation

¹Diagnosis of polycythemia vera requires meeting either all 3 major criteria, or the first 2 major criteria and the minor criterion.

RCM: Red cell mass; JAK2: Janus kinase 2.