Effect of fibrinolytic therapy on ST-elevation myocardial infarction clinical outcomes during the COVID-19 pandemic: A systematic review and meta-analysis

Table 2 Baseline characteristics of the included subjects

Ref.	Study group	Age, years (SD)	Male, n (%)	Hypertension, n (%)	Diabetes mellitus, n (%)	Hyperlipidemia, n (%)	Smoking, n (%)
Daoulah et al[15]	Pandemic period STEMI	55.4 (11.8)	454 (90.8)	229 (46.7)	257 (52.1)	190 (38.9)	213 (43)
	Pre-pandemic period STEMI	56.5 (12.8)	1123 (87.5)	599 (47.6)	632 (50.4)	450 (35.8)	318 (41.6)
Leng et al[16]	Pandemic period STEMI	63.13 (13.6)	131 (79.9)	N/A	N/A	N/A	N/A
	Pre-pandemic period STEMI	62.21 (13.14)	178 (73.9)	N/A	N/A	N/A	N/A
Song et al[17]	Pandemic period STEMI	61.6 (13.1)	59 (80.82)	43 (58.9)	16 (21.9)	39 (53.4)	36 (49.3)
	Pre-pandemic period STEMI	60.6 (13.9)	68 (71.57)	56 (59)	22 (23.2)	51 (53.7)	55 (57.9)
Wang et al[18]	Pandemic period STEMI	59.29 (11.46)	33 (89.18)	20 (54.05)	6 (16.21)	13 (35.13)	37 (100)
	Pre-pandemic period STEMI	55.49 (11.89)	35 (85.36)	18 (43.90)	5 (12.19)	15 (36.58)	31 (75.60)
Wu et al[19]	Pandemic period STEMI	65.1 (13.6)	1181 (73.81)	581 (36.31)	309 (19.31)	368 (23)	450 (28.12)
	Pre-pandemic period STEMI	65.76 (13.44)	11263 (71.98)	6060 (38.73)	3005 (19.20)	3645 (23.29)	4704 (30.06)
Xiang et al[20]	Pandemic period STEMI	61.59 (13.10)	7986 (75.94)	N/A	N/A	N/A	N/A
	Pre-pandemic period STEMI	62.86 (12.33)	11019 (75.29)	N/A	N/A	N/A	N/A
Zhang et al[21]	Pandemic period STEMI	N/A	N/A	N/A	N/A	N/A	N/A
	Pre-pandemic period STEMI	N/A	N/A	N/A	N/A	N/A	N/A
Huang et al[22]	Pandemic period STEMI	61	25 (80.6)	16 (51.6)	8 (25.8)	7 (22.6)	18 (58.1)
	Pre-pandemic period STEMI	60	25 (80.6)	18 (58.1)	6 (19.4)	8 (25.8)	20 (64.5)
Erol et al[23]	Pandemic period STEMI	59 (13)	552 (77.63)	221 (45.56)	151 (31.13)	108 (22.26)	248 (50.30)
	Pre-pandemic period STEMI	60 (14)	387 (79.79)	273 (38.39)	201 (28.27)	67 (9.4)	401 (56.39)
Mesnier et al[24]	Pandemic period STEMI	63.4 (12.5)	357 (74)	116 (24.11)	35 (7.27)	N/A	96 (19.95)
	Pre-pandemic period STEMI	64.4 (13.6)	509 (74)	139 (20.26)	55 (8.01)	N/A	131 (19.09)
Balghith[25]	Pandemic period STEMI	57.2 (12.6)	83 (90.21)	44 (54.32)	45 (48.91)	36 (39.13)	41 (44.56)
	Pre-pandemic period STEMI	51.3 (11.5)	81 (100)	38 (41.3)	41 (44.56)	31 (33.69)	35 (38.04)
Clifford et al[26]	Pandemic period STEMI	65 (12)	169 (71)	99 (51.29)	55 (28.49)	86 (44.55)	53 (27.46)
	Pre-pandemic period STEMI	64 (13)	135 (70)	123 (51.68)	54 (22.68)	99 (41.5)	93 (39.07)
Rodríguez-Leor et al[27]	Pandemic period STEMI	63.1 (12.5)	786 (78.4)	520 (51.9)	226 (22.6)	466 (46.7)	442 (44.6)
	Pre-pandemic period STEMI	63.7 (13.2)	1023 (78.4)	647 (50)	224 (25.2)	592 (45.8)	581 (45.7)
Calvão et al[28]	Pandemic period STEMI	63.3 (12.7)	56 (78.9)	49 (69.01)	23 (32.39)	38 (53.52)	40 (56.33)
	Pre-pandemic period STEMI	65.7 (12.8)	60 (75)	48 (60)	26 (32.5)	49 (57.5)	39 (48.75)

N/A: Not available; STEMI: ST-elevation myocardial infarction.