Observational Study
Copyright ©The Author(s) 2023.
World J Cardiol. May 26, 2023; 15(5): 262-272
Published online May 26, 2023. doi: 10.4330/wjc.v15.i5.262
Table 3 Joint effects for interaction of sex and apparent treatment resistant hypertension, and age and apparent treatment resistant hypertension on cardiovascular disease risk
aTRH (No)
aTRH (Yes)

HR
(95%CI)
HR
(95%CI)
HR (95%CI) by sex
SexFemaleReference1.67(1.45, 1.91)1.64 (1.43, 1.88)
Male1.25(1.16, 1.34)1.39(1.12, 1.56)1.13 (1.01, 1.27)
HR (95%CI) (M vs F)1.25(1.16, 1.35)0.80(0.66, 0.97)
RERI (95%CI)-0.52(-0.75, 0.25)
Interaction of sex and aTRH on CVD: P < 0.0001
HR (95%CI) by age
Age< 65Reference1.56(1.42, 1.71)1.53 (1.32, 1.77)
≥ 651.38(1.31, 1.45)1.61(1.48, 1.73)1.18 (1.05, 1.32)
≥ 65 vs < 651.37(1.28, 1.47)1.05(0.87, 1.27)
RERI (95%CI)-0.339(-0.61, 0.06)
Interaction of age and aTRH on CVD: P = 0.0326