Safety and efficacy of balloon angioplasty compared to stent-based-strategies with pulmonary vein stenosis: A systematic review and meta-analysis

Table 3 Follow up characteristics after revascularization

Ref.	Antiplatelet therapy	Imaging modalities	Restenosis definition
Qureshi et al[19], 2003	NR	CT-scans every 3 mo	PV narrowing > 70% of the original PV lumina
Prieto et al[7], 2008	NR	CT-scans, lung perfusion scans at 3-12-24 mo	NR
Neumann et al[8], 2009	ASA+Clopidogrel+Coumadin for 3 mo	CT-scans, lung perfusion scans every 3 mo	PV narrowing > 70%of the original PV lumina before PVI
Fender et al[20], 2016	Coumadin+Clopidogrel	CT-scans, lung perfusion scans at 3-12-24 mo	PV narrowing > 75% in the previously treated PV
Cory et al[5], 2017	NA	Angiography	Vein loss defined as PV atresia or PVs of uncertain status in deceased patients
Schoene et al[15], 2018	ASA 4 weeks+Clopidogrel 6 mo+Coumadin or DOACs	CT-scans, MR imaging	PV narrowing > 70% in the previously treated PV
Kurita et al[9], 2019	ASA, Ticlopidin, Warfarin	CT or angiography	In stent restenosis: ≥ 50% luminal narrowing
Suntharos et al[8], 2019	Anticoagulation followed by low-dose aspirin	CT-scans, lung perfusion scans, angiography based on intervention-3 mo, 6 mo, 1yr	Severe restenosis/concern for progression to total occlusion

ASA: Acetyl salicylic acid; CT: Computed tomography; NA: Not available; NR: Not reported; PV: Pulmonary vein; PVI: Pulmonary vein isolation.