Observational Study
Copyright ©The Author(s) 2022.
World J Cardiol. Aug 26, 2022; 14(8): 462-472
Published online Aug 26, 2022. doi: 10.4330/wjc.v14.i8.462
Table 3 Comparison of cardiometabolic and glycaemic variables for men depending upon different categories of beta-cell function (oral disposition index)
Variable
Quartile 4 oDI > 75th percentile of total cohort n = 158
Quartile 2-3 oDI 25th to 75th percentile of total cohort n = 319
Quartile 1 oDI < 25th percentile of total cohort n = 158
P valuea
Age (yr)33.1 ± 5.133.8 ± 4.935.0 ± 5.30.003
Family H/O diabetes 48 (30.4)124 (38.9)73 (46.2)0.015
BMI (kg/m2) 25.0 ± 3.9 25.9 ± 3.827.2 ± 3.7< 0.001
BMI ≥ 25 kg/m275 (47.5)195 (61.1)118 (74.7)< 0.001
Waist circumference (cm)91.8 ± 9.593.6 ± 9.597.6 ± 9.1< 0.001
Waist circumference ≥ 90 cm93 (58.9)224 (70.2)131 (84.0)< 0.001
Systolic BP ≥ 140 mmHg9 (5.7)20 (6.3)17 (10.8)0.135
Diastolic BP ≥ 90 mmHg15 (9.5)53 (16.6)43 (27.4)< 0.001
Hypertension19 (12.0)56 (17.6)48 (30.6)< 0.001
Total cholesterol ≥ 5.2 mmol/L32 (20.3)106 (33.3)55 (34.8)0.005
LDL-C ≥ 2.6 mmol/L79 (50.0)196 (61.6)103 (65.2)0.013
HDL-C < 1.03 mmol/L80 (50.6)163 (51.3)93 (58.9)0.232
Triacylglycerol ≥ 1.7 mmol/L51 (32.3)139 (43.7)91 (57.6)< 0.001
The metabolic syndrome42 (26.6)118 (37.0)98 (62.0)< 0.001
HOMA-IR (mmol/L × µIU/mL)2.1 (1.2-3.0)2.6 (1.9-3.7)4.0 (2.7-6.0)< 0.001
Insulinogenic index (pmolins/mmolglu)410.5 (257.1-651.6)215.6 (146.6-299.4)85.6 (51.2-127.7)< 0.001
Disposition index (l/mmolglu)6.1 (4.9-9.1)2.6 (2.0-3.3)0.8 (0.5-1.2)< 0.001
Dysglycaemia57 (36.1)147 (46.1)127 (80.4)< 0.001