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©The Author(s) 2022.
World J Cardiol. May 26, 2022; 14(5): 282-296
Published online May 26, 2022. doi: 10.4330/wjc.v14.i5.282
Published online May 26, 2022. doi: 10.4330/wjc.v14.i5.282
Table 1 Top 10 differentially expressed genes in the dilated cardiomyopathy group vs normal group
| Expression | Gene symbol | Description | logFC | adj. P value |
| ASPN | Asporin | 2.31 | 3.05E-22 | |
| NPPA | Natriuretic peptide A | 2.08 | 1.26E-11 | |
| LUM | Lumican | 1.87 | 4.56E-18 | |
| MXRA5 | Matrix remodeling associated 5 | 1.43 | 5.47E-14 | |
| UP | HBB | Hemoglobin subunit beta | 1.20 | 3.08E-05 |
| COL1A2 | Collagen type I alpha 2 chain | 1.09 | 1.37E-10 | |
| COL3A1 | Collagen type III alpha 1 chain | 1.05 | 2.39E-07 | |
| OGN | Osteoglycin | 1.01 | 5.38E-09 | |
| FRZB | Frizzled related protein | 0.99 | 1.08E-13 | |
| EIF1AY | Eukaryotic translation initiation factor 1A Y-linked | 0.96 | 1.33E-02 | |
| MYOT | Myotilin | -1.89 | 1.70E-13 | |
| ANKRD2 | Ankyrin repeat domain 2 | -1.44 | 3.00E-08 | |
| PLA2G2A | Phospholipase A2 group IIA | -1.35 | 4.43E-07 | |
| MYH6 | Myosin heavy chain 6 | -1.35 | 1.80E-05 | |
| SERPINA3 | Serpin family A member 3 | -1.28 | 1.75E-18 | |
| Down | CYP4B1 | Cytochrome P450 family 4 subfamily B member 1 | -1.20 | 1.06E-07 |
| FCN3 | Ficolin 3 | -1.19 | 2.48E-13 | |
| CNN1 | Calponin 1 | -1.16 | 2.09E-10 | |
| PTX3 | Pentraxin 3 | -1.13 | 1.27E-04 | |
| NRAP | Nebulin related anchoring protein | -1.11 | 1.30E-03 |
- Citation: Liu Z, Song YN, Chen KY, Gao WL, Chen HJ, Liang GY. Bioinformatics prediction of potential mechanisms and biomarkers underlying dilated cardiomyopathy. World J Cardiol 2022; 14(5): 282-296
- URL: https://www.wjgnet.com/1949-8462/full/v14/i5/282.htm
- DOI: https://dx.doi.org/10.4330/wjc.v14.i5.282