Copyright
©The Author(s) 2022.
World J Cardiol. Apr 26, 2022; 14(4): 250-259
Published online Apr 26, 2022. doi: 10.4330/wjc.v14.i4.250
Published online Apr 26, 2022. doi: 10.4330/wjc.v14.i4.250
Ref. | Design | Procedure | Definition of vasoplegia | Total sample | Vasoplegia (%) | ACEI (%) |
Tuman et al[14] | Case-control | Coronary artery and/or valve surgery requiring CPB | Post-CPB ≥ 2 vasoconstrictors with adequate cardiac output | 4301 | 4.5 | 12.1 |
Bruce et al[16] | Case-control | Cardiac surgery requiring CPB | MAP ≤ 50 mmHg, indexed SVR ≤ 1400 dynes s/cm5/m2, cardiac index ≥ 2.2 L/min/m2, requiring norepinephrine infusion | 188 | 34.0 | 42.0 |
Carrel et al[17] | Case-control | CABG or AVR | SVR < 600 dynes s/cm5 with adequate cardiac output | 800 | 7.5 | 43.1 |
Mekontso-Dessap et al[7] | Case-control | CABG | MAP < 70 mmHg, indexed SVR ≤ 1400 dynes s/cm5/m2, normal cardiac output, requiring vasoconstrictor | 108 | 33.3 | 31.5 |
Sun et al[15] | Case-control | CABG | MAP ≤ 70 mmHg, indexed SVR ≤ 1400 dynes s/cm5/m2, cardiac index ≥ 2.5 L/min/m2, and central venous pressure ≥ 10 mmHg | 696 | 4.7 | 38.5 |
Levin et al[2] | Case-control | Cardiac surgery | Epinephrine/norepinephrine (≥ 150 ng/kg/min), dopamine (≥ 10 μg/kg/min) or vasopressin (≥ 4 U/h) | 2823 | 20.4 | 19.7 |
Shahzamani et al[6] | Case-control | CABG | MAP < 65 mmHg, normal cardiac output, requiring vasoconstrictor | 300 | 17.0 | 64.0 |
Radaelli et al[19] | Case-control | Cardiac surgery | 3 of these 4: MAP < 65 mmHg, indexed SVR ≤ 1600 dynes s/cm5/m2, cardiac index ≥ 2.5/min/m2, and requirement of norepinephrine (> 0.03 μg/kg/min) or vasopressin | 3139 | 32.5 | 52.1 |
Suga et al[5] | Case-control | CABG | Inotropic support post-CABG | 562 | 11.7 | 9.1 |
Miceli et al[18] | Case-control | CABG | Inotropic support post-CABG | 2655 | 43.5 | 51.0 |
Pigot et al[21] | RCT | CABG | Inotropic support post-CABG | 40 | 15.0 | 100 |
van Diepen et al[20] | RCT | CABG or valve surgery | MAP < 60 mmHg requiring vasopressor administration for at least 4 h and a central venous pressure ≥ 8 mmHg | 121 | 29.8 | 76.9 |
- Citation: Noubiap JJ, Nouthe B, Sia YT, Spaziano M. Effect of preoperative renin-angiotensin system blockade on vasoplegia after cardiac surgery: A systematic review with meta-analysis. World J Cardiol 2022; 14(4): 250-259
- URL: https://www.wjgnet.com/1949-8462/full/v14/i4/250.htm
- DOI: https://dx.doi.org/10.4330/wjc.v14.i4.250