Dispersion of ventricular repolarization: Temporal and spatial

Figure 2 Realistic activation sequence, action potential duration distribution and end-of-repolarization sequence in the rabbit heart ventricles’ model, simulated from intramural and epicardial measurements[56]. The middle transversal and longitudinal cross-sections of the model and the corresponding T-vector projections are shown. Transmural, apicobasal, anterior-posterior and left-to-right gradients in activation times, action potential duration and end-of-repolarization times, reconstructed from experimental data, are presented. A and B – the regions of the earliest and the latest end-of-repolarization, correspondingly. T-vector direction is parallel but opposite to the general direction of repolarization sequence.