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Copyright ©The Author(s) 2020.
World J Cardiol. Aug 26, 2020; 12(8): 409-418
Published online Aug 26, 2020. doi: 10.4330/wjc.v12.i8.409
Figure 3
Figure 3 Theoretical bench to bedside flow chart for some commonly encountered clinical scenarios. 1Cytoskeleton (e.g., Rho kinase activity), contractile apparatus (e.g., Titin phosphorylation), mitochondrial energetics, AGE. 2Ventricular atrial coupling; Microvasculature; Pericardial restraint; Chronotropic reserve. ADHF: Acute decompensated heart failure; AGE: Advanced glycation end products; ANP: Atrial natriuretic peptide; BNP: Brain natriuretic peptide; IL-1α: Interleukin 1 alpha; CRI: Chronic renal impairment/insufficiency; IS: Indoxyl sulphate; PBUT: Protein bound uremic toxins; PCS: P-cresyl sulphate; RAAS: Renin angiotensin aldosterone syndrome; SNSA: Sympathetic nervous system activity.