Transradial vs transfemoral secondary access outcomes in transcatheter aortic valve implantation: A systematic review and meta-analysis

Table 2 Demographic comparison based on secondary access of matched/adjusted data (if available)

	Junquera et al[2]		Fernandez-Lopez et al[6]		Jackson et al[5]		Allende et al[4]		Curran et al[3]
	TFSA (n = 2978)	TRSA (n = 928)	TFSA (n = 194)	TRSA (n = 217)	TFSA (n = 64)	TRSA (n = 135)	TFSA (n = 335)	TRSA (n = 127)	TFSA (n = 41)	TRSA (n = 46)
Baseline characteristics of patients
Age	81 ± 4	81 ± 8	83 ± 7	82 ± 6	82 ± 6	82 ± 7	79 ± 8	80 ± 9	80 ± 10	80 ± 5
%Male	52.60%	53.20%	44.80%	53.50%	57.00%	43.00%	45.00%	61.00%	31.70%	52.20%
Baseline comorbidities
Diabetes	26.90%	27.00%	31.40%	24.40%	20.00%	20.00%	35.00%	31.00%	30.00%	26.10%
HTN	-	-	56.70%	55.30%	-	-	88.00%	84.00%	92.50%	80.40%
CAD	51.20%	50.30%	-	-	53.00%	52.60%	67.00%	63.00%	-	-
Previous CABG	19.80%	19.60%	4.10%	6.00%	20.00%	19.30%	39.00%	33.00%	17.10%	17.40%
AFib	33.50%	34.70%	27.80%	33.60%	25.00%	25.00%	17.00%	20.00%	-	-
PVD	16.30%	19.20%	13.40%	14.30%	18.00%	26.70%	40.00%	24.00%	-	-
Prior CVA	-	-	10.30%	10.60%	17.00%	16.30%	19.00%	16.00%	-	-
eGFR < 60 mL/min/1.73 m2	67.60%	69.40%	-	-	-	-	57.00%	51.00%	-	-
COPD/Pul disease	21.30%	20.90%	11.90%	13.40%	25.00%	25.90%	29.00%	25.00%	20.00%	13.00%
STS-PROM score	4.5	4.7	5.0 ± 3.0	4.8 ± 3.6	-	-	7.1 ± 4.5	7.2 ± 5.0	9.0 ± 7.8	7.2 ± 7.5
Valve type
Balloon-expandable	60.00%	63.50%	NA	NA	NA	NA	96.00%	88.00%	NA	NA
Self-expandable	40.00%	36.50%	NA	NA	NA	NA	3.00%	10.00%	NA	NA
1° Access
TFPA	88.50%	89.90%	100%	100%	100%	85.20%	30.80%	93.00%	100%	100%
Non-TFPA	11.50%	10.10%	0	0	0	14.80%	69.20%	7.00%	0	0
Transapical	9.10%					3.70%	58.20%	6.00%
Transaortic	1.90%					8.80%	10.70%	1.00%
Subclavian	1.50%					2.20%	0.30%	0
Transcarotid	4.06%					0	0	0
Transcaval	0.12%					0	0	0

TFSA: Transfemoral secondary access; TRSA: Transradial secondary access; HTN: Hypertension; CAD: Coronary artery disease; CABG: Coronary artery bypass graft; AFib: Atrial fibrillation; PVD: Peripheral vascular disease; CVA: Cerebrovascular event; eGFR: Estimated glomerular filtration rate; COPD: Chronic obstructive pulmonary disease; STS-PROM: Society of thoracic surgeons predicted risk of mortality; TFPA: Transfemoral primary access.