Prevalence and clinical characteristics associated with left atrial thrombus detection: Apixaban

Table 2 Univariate and multivariate predictors of left atrial appendage thrombus

Apixaban
Variable	Unadjusted (univariate analysis)			Adjusted (multivariate analysis)
	OR	95%CI	P-value	OR	95%CI	P-value
CHF	1.440	0.31-6.60	0.6388
Hypertension	1.933	0.24-15.87	0.5396
Age > 65	3.453	0.41-29.20	0.2552
Age > 75	0.578	0.07-4.92	0.6160
Diabetes	1.425	0.27-7.58	0.6778
Stroke	2.177	0.25-18.85	0.4800
Vascular disease	1.293	0.15-11.19	0.8152
CHA2DS2-VASc	1.261	0.80-2.00	0.3240
Gender (female)	0.631	0.12-3.32	0.5866
Persistent AF	7.639	1.44-40.51	0.01691	7.427	1.02-53.92	0.0474
LVEF < 30%	4.725	1.01-22.17	0.04891	0.726	0.10-5.12	0.7480
LVEF < 50%2	2.667	0.58-12.23	0.2069
Severe left atrial dilation1	8.877	1.27-61.85	0.02751	5.901	0.69-50.62	0.1054
LAA velocity (decrease)1	1.110	1.031-1.19	0.00321	1.086	1.010-1.187	0.0489
LAA velocity < 40 cm/s2	14.215	1.68-120.40	0.01492

¹Significant factor in the univariate model which is used in the multivariate model;

²Significant factor in the univariate model but not considered in the multivariate model. AF: Atrial fibrillation; CHF: Congestive heart failure; CI: Confidence interval; LAA: Left atrial appendage; LVEF: Left ventricular ejection fraction; OR: Odds ratio.