Surgical left atrial appendage occlusion during cardiac surgery: A systematic review and meta-analysis

Table 1 Characteristics of the included studies

Study, yr	Country	Study period	Study design	Sample size		Cardiac surgery type	Follow up period (mo)
				s-LAAO	No occlusion
García-Fernández et al, 2003[3]	Spain	2003	retrospective	58	147	MVS	69.4 ± 67
Healey et al, 2005[7]	Germany	2001-2002	RCT	52	25	CABG	13 ± 7
Nagpal et al, 2009[8]	Canada	2007-2007	RCT	22	21	MVS	<1
Whitlock et al, 2013[9]	Canada	2009-2010	RCT	26	25	CABG and VS	1
Zapolanski et al, 2013[4]	United States	2005-2012	retrospective	808	969	CABG and VS	NR
Kim et al, 2013[6]	United States	2001-2010	retrospective	631	631	CABG and MVS	1
Lee et al, 20141[5]	Korea	1999-2011	retrospective	119	119	MVS with AF ablation	63 ± 44
Melduni et al, 20171[10]	United States	2000-2005	prospective	461	461	CABG and VS	109.2
Elbadawi et al, 20172[11]	United States	1998-2013	retrospective	652	652	VS	In-hospital
Elbadawi et al, 2017[12]	United States	2004-2013	retrospective	2519	12595	CABG	In-hospital
Friedman et al, 2018[14]	United States	2011-2012	retrospective	3892	6632	CABG, MVS, AVS	31.2
Yao et al, 20181[13]	United States	2009-2017	retrospective	4295	4295	CABG, VS	25.2 ± 22.8

RCT: Randomized controlled trial; CABG: Coronary artery bypass grafting; VS: Valvular surgery; MVS: Mitral valve surgery; AVS: Aortic valve surgery; AF: Atrial fibrillation. ¹Propensity match studies. ²Case matching study.