Role of microRNAs in translation regulation and cancer

doi:10.4331/wjbc.v8.i1.45

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Feb 26, 2017 (publication date) through Nov 30, 2024

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World Journal of Biological Chemistry

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1949-8454

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Biol Chem. Feb 26, 2017; 8(1): 45-56
Published online Feb 26, 2017. doi: 10.4331/wjbc.v8.i1.45

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Figure 3 Roles of microRNAs in cancer. miRNAs suppress the expression of their target genes. An oncogenic miRNA, termed oncomiR, can repress the translation of a tumor suppressor gene, stimulating tumorigenesis and leading to tumor formation. Conversely, a tumor suppressor miRNA is able to inhibit the expression of oncogenes, blocking the tumorigenesis process and consequently the development of cancer.

Citation: Oliveto S, Mancino M, Manfrini N, Biffo S. Role of microRNAs in translation regulation and cancer. World J Biol Chem 2017; 8(1): 45-56
URL: https://www.wjgnet.com/1949-8454/full/v8/i1/45.htm
DOI: https://dx.doi.org/10.4331/wjbc.v8.i1.45