Copyright
©The Author(s) 2017.
World J Biol Chem. Feb 26, 2017; 8(1): 45-56
Published online Feb 26, 2017. doi: 10.4331/wjbc.v8.i1.45
Published online Feb 26, 2017. doi: 10.4331/wjbc.v8.i1.45
Figure 3 Roles of microRNAs in cancer.
miRNAs suppress the expression of their target genes. An oncogenic miRNA, termed oncomiR, can repress the translation of a tumor suppressor gene, stimulating tumorigenesis and leading to tumor formation. Conversely, a tumor suppressor miRNA is able to inhibit the expression of oncogenes, blocking the tumorigenesis process and consequently the development of cancer.
- Citation: Oliveto S, Mancino M, Manfrini N, Biffo S. Role of microRNAs in translation regulation and cancer. World J Biol Chem 2017; 8(1): 45-56
- URL: https://www.wjgnet.com/1949-8454/full/v8/i1/45.htm
- DOI: https://dx.doi.org/10.4331/wjbc.v8.i1.45