Arctic ground squirrel neuronal progenitor cells resist oxygen and glucose deprivation-induced death

Figure 6 By 48 and 72 h after re-oxygenation the ratio of neuronal progenitor cells to total cells increases slightly or remains the same. AGS NPCs cultured for 21 d in vitro were deprived of oxygen followed by 48 h (A, B) or 72 h (C, D) of re-oxygenation. After 48 h of reoxygenation, the proportion of NPCs increased relative to total cells because the number of dividing NPCs increased (B). After 72 h the proportion of NPCs was sustained (C) because division of NPCs declined less than other cell lineages (D). ^aP < 0.05 compared to control, t-test. Mean ± SD. AGS: Arctic ground squirrel; NPCs: Neuronal progenitor cells.