Arctic ground squirrel neuronal progenitor cells resist oxygen and glucose deprivation-induced death

Figure 3 ATP (shown as relative luminescence units) declines in arctic ground squirrel neuronal progenitor cells during oxygen and glucose deprivation. NPCs at 14 d in vitro deprived for 48 h followed by 24 h resource replacement lost ATP when deprived of oxygen or oxygen and glucose (A). ATP recovered within 24 h of reoxygenation or reperfusion (modeled by return of oxygen and glucose) (B). Horizontal lines P < 0.05; ANOVA followed by a Holm-Sidak test. Mean + SD. Only differences relative to control are shown. OGD: Oxygen and glucose deprivation; NPCs: Neuronal progenitor cells.