Apoptosis induced by Fas signaling does not alter hepatic hepcidin expression

Figure 2 Caspase-3 activity, the expression of acute phase response and mouse hepcidin genes in the liver: C57BL/6NCR strain male mice, which were injected with Jo2 antibody (0. 2 µg/g b.w.) or saline (as control), were sacrificed 1 h later. A: Caspase-3 activity was measured, as described in the ‘Materials and Methods’ section. B-E: IL-6 (B), SAA3 (C), hepcidin-1 (D) and hepcidin-2 (E) gene expression was determined by qPCR, and mRNA expression in Jo2-treated mice expressed as fold change of that in control mice.