Effects of acute doxorubicin treatment on hepatic proteome lysine acetylation status and the apoptotic environment

Figure 6 Protein content of procaspase-12 and 40 kDa cleavage product. Doxorubicin (Dox) treatment did not significantly affect the hepatic content of procaspase-12. However, Dox did induce activation of caspase-12 leading to increased content of the 40 kDa cleavage product. Representative Western blot shows the 50 kDa procaspase-12 and the 40 kDa cleaved product. ^aP < 0.050, Dox vs control.