KAPtain in charge of multiple missions: Emerging roles of KAP1

Table 3 Mouse models illustrating the physiological functions of Kap1

Animal model	Phenotype	Ref.
Kap1 knockout mice	Embryonic lethal prior to gastulation	[19]
Hemato-specific Kap1 knockout mice	Impaired erythropoiesis	[71,100]
T-cell-specific Kap1 knockout mice	Defective T-cell differentiation	[48,98]
B-cell-specific Kap1 knockout mice	Defective B-cell differentiation	[99]
Tamoxifen-inducible-germ cell-lineage-specific Kap1 depletion mice	Impaired spermatogenesis	[101]
Liver-specific Kap1 knockout mice	Male-predominant steatosis and hepatic adenoma	[120]
Kap1 knockout in mice forebrain	Anxiety-like-behavior and cognitive impairments	[103]