Endoglin in liver fibrogenesis: Bridging basic science and clinical practice

Figure 2 Sequence alignment of rat endoglin and betaglycan. The protein sequences of rat endoglin and betaglycan were aligned using the ClustalW2 algorithm. Respective sequences of rat endoglin (AAS67893) and betalycan (AAA42236.1) were taken from the GenBank. Please note the high degree of similarity of both proteins at their C-termini. Fully conserved aa in endoglin are marked by asterisk (*), positions that carry aa with strongly similar properties by a colon (:) and positions with weakly similar properties by a period (.), respectively. Please note that the highest degree of homology is found at the C-terminal regions that encompass the cytosolic part of endoglin