Galectin-1-mediated biochemical controls of melanoma and glioma aggressive behavior

Figure 4 How galectin-1 is involved in chemoresistance of cancer cells. ATF3 and ATF6: Activating transcription factor 3 and 6; DUSP5: Dual specificity protein phosphatase 5; GADD153 and GADD45A: Growth arrest and DNA damage inducible protein 153 and 45 α; GRP78 and GRP94: Glucose-regulated protein 78 and 94; HSP70: Heat shock protein 70; IRE1-α: Endoplasmic reticulum to nucleus signaling 1 α; ORP150: Oxygen-related protein 150; PERK: Protein kinase RNA-like endoplasmic reticulum kinase; TF: Transcription factor; XBP1: X-box-binding protein 1.