Galectin-1-mediated biochemical controls of melanoma and glioma aggressive behavior

Figure 3 Galectin-1-mediated control of angiogenesis. ATF3: Activating transcription factor 3; BEX2: Brain-expressed X-linked 2; CTGF: Connective tissue growth factor; CYR61: Cysteine-rich angiogenic inducer 61; Erk: Extracellular signal-regulated kinase; GRP78 and GRP94: Glucose-regulated protein 78 and 94; IRE1-α: Endoplasmic reticulum to nucleus signaling 1 α; MDG1: Microvascular endothelial differentiation gene 1; Mek: Mitogen-activated protein kinase kinase; ORP150: Oxygen-related protein 150; Raf: Homolog to murine v-raf leukemia oncogene serine/threonine kinase; Ras: Rat sarcoma virus oncogene protein; TF: Transcription factor; VEGF: Vascular endothelial growth factor; VEGFR: VEGF receptor; XBP1: X-box-binding protein 1. EC: Endothelial cell.