p53 in stem cells

Table 1 p53 target genes regulating stem cell behavior

Gene	Regulation	Cell type	Effect	Ref.
nanog	Repression	mESCs	Pro-differentiation	[2]
4-Oct	Repression	mESC	Pro-differentiation	[17]
wnt3, wnt3A, wnt 8a, wnt8b, wnt9A, fzd1, fzd 2, fzd6, fzd8, fzd10, lef1	Activation	mESCs	Anti-differentiation	[31]
miRNA-200c	Activation	Mammary epithelial cells	Inhibition of epithelial-mesenchymal transition	[66]
osterix	Repression	Mesenchymal stem cells	Inhibition of osteogenic differentiation	[80]
runx2	Repression	Mesenchymal stem cells	Inhibition of osteogenic differentiation	[81]
pparγ	Repression	Mesenchymal stem cells	Inhibition of adipogenic differentiation	[82]
duoxa1; duox1	Activation	Neural stem cells	Activation of neurogenesis	[100]
gfi1	Activation	Hematopoietic stem cells	Maintenance of quiescence	[117]
necdin	Activation	Hematopoietic stem cells	Maintenance of quiescence	[117]
p21	Activation	Hematopoietic stem cells	Regulation of HSC amount	[117]