Regulation of heme oxygenase expression by alcohol, hypoxia and oxidative stress

Figure 7 Heme oxygenase expression in ARNT (hypoxia inducible factor-1β) knockout mice. Heme oxygenase (HO)-1 mRNA expression in the livers of (A) ARNT floxed control mice and (B) liver-specific ARNT heterozygous knockout mice (ARNT^+/-/Alb-Cre^+/-), fed with plain water or 10% ethanol in drinking water for 7 d was measured by real-time polymerase chain reaction. HO expression in alcohol-treated mice was expressed as fold expression of that in mice fed with plain water. ^bP < 0.01.