Protein arginine methyltransferase 6 is a novel substrate of protein arginine methyltransferase 1

Figure 7 The mutation sites of protein arginine methyltransferase 6 and corresponding residues on protein arginine methyltransferase 1. A: Sequence alignment of protein arginine methyltransferase (PRMT) 1 and PRMT6 showing the corresponding mutation sites; B: The corresponding mutation sites are highlighted on PRMT6 structure. hPRMT6 monomer (PDB: 4Y30) is shown in a cartoon model. The mutation sites of PRMT6 with their corresponding residues on PRMT1 and the S-Adenosyl-L-homocysteine molecule are shown in a stick model.