Important relationships between Rab and MICAL proteins in endocytic trafficking

doi:10.4331/wjbc.v1.i8.254

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Aug 26, 2010 (publication date) through Nov 7, 2024

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World Journal of Biological Chemistry

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1949-8454

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Biol Chem. Aug 26, 2010; 1(8): 254-264
Published online Aug 26, 2010. doi: 10.4331/wjbc.v1.i8.254

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Figure 3 MICAL-L1 and MICAL-L2 regulate endocytic recycling. A: MICAL-L1 recruits Eps15 homology domain 1 (EHD1) and Rab8A to endocytic membranes and regulates recycling of transferrin and β1 integrin receptors; B: MICAL-L2/Rab13 interactions control transport of claudin-1 and occludin to the plasma membrane, whereas MICAL-L2/Rab8 complexes regulate recycling of E-cadherin. EE/SE: Early endosome/sorting endosome; RE: Recycling endosome; AEE: Apical early endosome; CRE: Common recycling endosome; ARE: Apical recycling endosome.

Citation: Rahajeng J, Giridharan SSP, Cai B, Naslavsky N, Caplan S. Important relationships between Rab and MICAL proteins in endocytic trafficking. World J Biol Chem 2010; 1(8): 254-264
URL: https://www.wjgnet.com/1949-8454/full/v1/i8/254.htm
DOI: https://dx.doi.org/10.4331/wjbc.v1.i8.254