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World J Biol Chem. May 26, 2010; 1(5): 69-80
Published online May 26, 2010. doi: 10.4331/wjbc.v1.i5.69
Published online May 26, 2010. doi: 10.4331/wjbc.v1.i5.69
Figure 7 Possible role of secreted protein, acidic and rich in cysteine (SPARC) in cardiac healing and remodeling after MI.
SPARC regulates collagen maturation by direct interaction with collagen type I fibers and regulation of fibronectin matrix assembly. SPARC mediates TGF-β1 signaling, which is involved in wound healing and collagen production, thereby regulating cardiac healing and remodeling.
- Citation: Matsui Y, Morimoto J, Uede T. Role of matricellular proteins in cardiac tissue remodeling after myocardial infarction. World J Biol Chem 2010; 1(5): 69-80
- URL: https://www.wjgnet.com/1949-8454/full/v1/i5/69.htm
- DOI: https://dx.doi.org/10.4331/wjbc.v1.i5.69