Editorial
Copyright ©2010 Baishideng Publishing Group Co.
World J Biol Chem. May 26, 2010; 1(5): 69-80
Published online May 26, 2010. doi: 10.4331/wjbc.v1.i5.69
Figure 7
Figure 7 Possible role of secreted protein, acidic and rich in cysteine (SPARC) in cardiac healing and remodeling after MI. SPARC regulates collagen maturation by direct interaction with collagen type I fibers and regulation of fibronectin matrix assembly. SPARC mediates TGF-β1 signaling, which is involved in wound healing and collagen production, thereby regulating cardiac healing and remodeling.