Role of matricellular proteins in cardiac tissue remodeling after myocardial infarction

doi:10.4331/wjbc.v1.i5.69

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May 26, 2010 (publication date) through Nov 7, 2024

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World Journal of Biological Chemistry

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1949-8454

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Biol Chem. May 26, 2010; 1(5): 69-80
Published online May 26, 2010. doi: 10.4331/wjbc.v1.i5.69

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Figure 2 Possible role of osteopontin (OPN) in cardiac healing and remodeling after MI. OPN modulates various functions of macrophages, such as migration, phagocytosis, and pro-inflammatory cytokine production. OPN also regulates proliferation and adhesion of fibroblasts. Moreover, OPN modulates myofibroblast differentiation and function, thereby promoting collagen synthesis and organization.

Citation: Matsui Y, Morimoto J, Uede T. Role of matricellular proteins in cardiac tissue remodeling after myocardial infarction. World J Biol Chem 2010; 1(5): 69-80
URL: https://www.wjgnet.com/1949-8454/full/v1/i5/69.htm
DOI: https://dx.doi.org/10.4331/wjbc.v1.i5.69