Editorial
Copyright ©2010 Baishideng Publishing Group Co.
World J Biol Chem. May 26, 2010; 1(5): 69-80
Published online May 26, 2010. doi: 10.4331/wjbc.v1.i5.69
Figure 2
Figure 2 Possible role of osteopontin (OPN) in cardiac healing and remodeling after MI. OPN modulates various functions of macrophages, such as migration, phagocytosis, and pro-inflammatory cytokine production. OPN also regulates proliferation and adhesion of fibroblasts. Moreover, OPN modulates myofibroblast differentiation and function, thereby promoting collagen synthesis and organization.