Accurate resection of hilar cholangiocarcinoma using eOrganmap 3D reconstruction and full quantization technique

Table 1 Clinicopathological characteristics

Group	Sex (male/female)	Age (yr, mean ± SD)	Child–Pugh grade A/ B	Preoperative biliary drainage (yes/no)	Bismuth classification
					II	IIIa	IIIb	IV
Traditional group (n = 35)	15/20	58.55 ± 5.13	29/6	27/8	3	14	12	6
eOrganmap group (n = 38)	14/24	57.86 ± 5.67	34/4	30/8	1	16	13	8
χ2/t	0.275	0.544	0.675	0.035	1.338
P value	0.600	0.588	0.411	0.852	0.720

Table 2 Colligation condition during operation

Group	Traditional group (n = 35)	eOrganmap group (n = 38)	t/χ2	P value
Surgical procedure, n (%)			1.276	0.865
Left/right half liver + caudate lobectomy	23 (65.71)	27 (71.05)
Extended hemihepatectomy + caudate lobectomy	6 (17.14)	7 (18.42)
Liver trilobites + caudate lobectomy	2 (5.71)	2 (5.26)
Mesohepatectomy + caudate lobectomy	1 (2.86)	1 (2.63)
Other	3 (8.57)	1 (2.63)
Amount of intraoperative blood loss (mean ± SD, mL)	772.52 ± 112.13	553.62 ± 98.56	8.875	< 0.001
Operating time (mean ± SD, min)	645.29 ± 121.14	523.19 ± 103.15	4.648	< 0.001
Surgical margin pathology, n (%)			4.425	0.035
R0	29 (82.86)	37 (97.37)
R1	6 (17.14)	1 (2.63)
No. of lymph nodes dissected (mean ± SD)	9.12 ± 2.34	10.75 ± 2.58	2.819	0.006
Postoperative intestinal ventilation time (mean ± SD, d)	3.15 ± 1.02	2.65 ± 0.71	2.447	0.017
Postoperative hospital stay (mean ± SD, d)	22.64 ± 5.26	21.15 ± 4.87	1.257	0.213

Table 3 Postoperative complications, n (%)

Complication	Traditional group (n = 35)	eOrganmap group (n = 38)	χ2/Z	P value
Bile leakage	2 (5.71)	2 (5.26)	2.149	0.708
Abdominal fluid accumulation	3 (8.57)	3 (7.89)
Lung infection	3 (8.57)	2 (5.26)
Postoperative liver insufficiency	1 (2.86)	0 (0.00)
Stress ulcers	0 (0.00)	1 (2.63)
Total complication rate	9 (25.71)	8 (21.05)	0.222	0.638

Table 4 Total bilirubin and albumin levels (mean SD)

Time	TBIL (μmol/L)				ALB (g/L)
	Traditional group (n = 35)	eOrganmap group (n = 38)	t	P value	Traditional group (n = 35)	eOrganmap group (n = 38)	t	P value
T1	211.26 ± 15.31	209.58 ± 16.75	0.446	0.657	27.69 ± 4.13	23.16 ± 3.83	4.863	< 0.001
T2	165.28 ± 14.37	151.22 ± 12.58	4.456	< 0.001	29.39 ± 4.02	27.24 ± 4.12	2.253	0.027
T3	148.56 ± 17.28	140.37 ± 15.47	2.137	0.036	32.25 ± 3.23	30.22 ± 3.54	2.552	0.013
T4	128.62 ± 14.39	113.28 ± 15.27	4.408	< 0.001	34.66 ± 3.15	34.85 ± 4.41	0.210	0.834

TBIL: Total bilirubin; ALB: Albumin.

Table 5 Aspartate transaminase and alanine transaminase levels (mean SD)

Time	AST (U/L)				ALT (U/L)
	Traditional group (n = 35)	eOrganmap group (n = 38)	t	P value	Traditional group (n = 35)	eOrganmap group (n = 38)	t	P value
T1	112.17 ± 28.42	108.62 ± 30.23	0.516	0.608	122.15 ± 32.48	123.49 ± 31.58	0.179	0.859
T2	81.82 ± 10.67	75.38 ± 15.43	2.057	0.043	112.41 ± 24.15	101.21 ± 23.24	2.019	0.047
T3	75.25 ± 10.58	70.26 ± 6.38	2.462	0.016	108.36 ± 25.58	95.26 ± 26.31	2.154	0.035
T4	74.85 ± 9.20	56.12 ± 8.39	9.098	< 0.001	107.25 ± 28.56	82.28 ± 30.25	3.619	< 0.001

AST: Aspartate transaminase; ALT: Alanine transaminase.

Table 6 Stress response indicators (mean SD)

Indicators	Traditional group (n = 35)	eOrganmap group (n = 38)	χ2/Z	P value
IL-6 (pg/mL)
Pre-operation	50.89 ± 4.42	51.02 ± 4.16	0.130	0.897
Post-operation	61.66 ± 5.48	62.07 ± 5.14	1.243	0.742
Cor (ng/mL)
Pre-operation	62.35 ± 5.16	61.75 ± 5.58	0.476	0.636
Post-operation	72.22 ± 4.48	71.74 ± 5.03	0.429	0.669
NE (ng/L)
Pre-operation	161.53 ± 10.38	160.85 ± 9.47	0.293	0.771
Post-operation	177.25 ± 10.12	176.95 ± 9.13	0.133	0.894

Cor: Cortisol; IL-6: Interleukin-6; NE: Norepinephrine.