Hepatocellular carcinoma with child Pugh-A Cirrhosis treated with stereotactic body radiotherapy

Table 2 Summary of prospective stereotactic body radiotherapy studies in hepatocellular carcinoma patients with Child Pugh-A cirrhosis

Study	No of lesions	Median dose-fractionation	Median GTV (cc)	Local control	Overall survival	Grade 3+ toxicity	Median follow-up (m)
Mendez-Romero et al[17], 2006	111	5 Gy × 5	22.3	75%	75%, 40%	36%	12.9
				(22 mo)	(1, 2 yr)
Tse et al[24], 2008	21	6 Gy × 6	173	65%	48%	12%	17.6
				(1 yr)	(1 yr)
Lasley et al[25], 2012	39	16 Gy × 3	-	91%	72%	4.60%	33.3
				(2 yr)	(2 yr)
Bujold et al[33], 2013	102	6 Gy × 6	117	87%	55%, 34%	2%	31
				(1 yr)	(1 yr, 2 yr)
Current study	47	9 Gy × 5	23	98%	92%, 60%	None	24
				(2 yr)	(1 yr, 2 yr)

¹Study includes Child Pugh B patients. GTV: Gross tumor volume; cc: Cubic centimeters; Gy: Gray.