NOD2 mutations and colorectal cancer - Where do we stand?

Table 2 Nucleotide-binding and oligomerization-domain containing 2 polymorphisms and cancer risk: Results of meta-analysis

Meta-analysis		Liu et al[37] (2014)	Tian et al[41] (2010)
R702W
Variant genotypes vs homozygous wild-type	OR	1.32	1.59
	95%CI	1.01-1.72	1.09-2.32
	P value	0.04	0.02
G908R
Variant genotypes vs homozygous wild-type	OR	1.32	1.98
	95%CI	1.01-1.72	1.14-3.44
	P value	0.04	0.01
3020insC
Variant genotypes vs homozygous wild-type	OR	1.23	1.44
	95%CI	1.10-1.38	1.13-1.84
	P value	< 0.001	0.003
R702W/G908R/3020insC
Variant genotypes vs homozygous wild-type	OR	-	1.58
	95%CI	-	1.03-2.42
	P value	-	0.03

OR: Odds ratio.