Duodenal adenocarcinoma: Advances in diagnosis and surgical management

doi:10.4240/wjgs.v8.i3.212

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Mar 27, 2016; 8(3): 212-221
Published online Mar 27, 2016. doi: 10.4240/wjgs.v8.i3.212

Table 1 Histopathologic subtypes of duodenal adenocarcinoma

Phenotype	Histological characteristics	Histologically similar	Immunophenotype markers	Prognosis
Intestinal	Tubular/cribiforming glands lined by columnar neoplastic cells	Colonic adenocarcinoma	MUC2, CD10, CDX2	+
Gastric	Tubular/papillary proliferation with foveolar or pyloric-type differentiation	Gastric adenocarcinoma	MUC5AC, MUC6	-
Pancreaticobiliary	Simple glands of cuboidal/columnar cells with rounded pleomorphic nuclei; prominent desmoplastic stroma	Pancreatic and Extrahepatic bile duct adenocarcinoma	MUC1	-
Indeterminate	Poor differentiation	None	MUC1	-

Adapted from Ushiku et al[22].

Citation: Cloyd JM, George E, Visser BC. Duodenal adenocarcinoma: Advances in diagnosis and surgical management. World J Gastrointest Surg 2016; 8(3): 212-221
URL: https://www.wjgnet.com/1948-9366/full/v8/i3/212.htm
DOI: https://dx.doi.org/10.4240/wjgs.v8.i3.212