Copyright
©The Author(s) 2016.
World J Gastrointest Surg. Oct 27, 2016; 8(10): 660-669
Published online Oct 27, 2016. doi: 10.4240/wjgs.v8.i10.660
Published online Oct 27, 2016. doi: 10.4240/wjgs.v8.i10.660
Markers | Goblet cell carcinoid | Typical carcinoid | Adenocarcinoma |
CEA | + | - | + |
CK7 | + | - | + |
CK20 | + | - | + |
CDX2 | + | - | + |
CD56 | +/- | ++ | - |
CAM5.2 | + | - | + |
Synaptophysin | +/- | ++ | - |
Chromogranin A | +/- | ++ | - |
Β-Catenin (nuclear) | - | - | + |
p53 | +/- | - | ++ |
Ki67% | +/- | +/- | ++ |
MUC1 | - | - | ++ |
MUC2 | ++ | - | +/- |
E-cadherin expression | N | N | U |
MATH-1 expression | + | + | - |
KRAS mutation | - | - | + |
SMAD4 mutation | - | - | + |
Notch signaling inhibition | U | + | - |
MMR (MSH2, MSH6, MLH1, PMS2) | - | - | +/- |
- Citation: Shenoy S. Goblet cell carcinoids of the appendix: Tumor biology, mutations and management strategies. World J Gastrointest Surg 2016; 8(10): 660-669
- URL: https://www.wjgnet.com/1948-9366/full/v8/i10/660.htm
- DOI: https://dx.doi.org/10.4240/wjgs.v8.i10.660