Laparoscopic liver resection: Experience based guidelines

Table 5 Comparative studies of laparoscopic and open liver resection for colorectal liver metastases including more than 30 patients in each arm

Ref.	No. of patients		Blood loss (mean/median, mL)			Blood transfusion (%)			Conversion (%)	Complication (% )			Perioperative mortality (%)			5-yr overall survival (%)			5-yr recurrence free survival (%)
	LLR	OLR	LLR	OLR	P value	LLR	OLR	P value		LLR	OLR	P value	LLR	OLR	P value	LLR	OLR	P value	LLR	OLR	P value
Castaing et al[50]	60	60	NR	NR	-	15	36	0.007	10	27	28	NS	1.7	1.7	NS	64	56	NS	30	20	NS
Abu Hilal et al[51]	55	119	363	500	NR	3.6	NR	NR	12	15	20.2	NR	0	2	NR	NR	NR	NR	NR	NR	-
Cannon et al[52]	35	140	202	392	< 0.001	17	25	NS	NR	23	50	0.004	0	1.4	NS	36	42	NS	15	22	NS
Qiu et al[53]	30	140	215	390	< 0.001	10	25	< 0.05	6.6	26.2	55	< 0.001	0	0	NS	NR	NR	-	NR	NR	-
Guerron et al[54]	40	40	376	753	0.041	5	20	0.04	5	15	20	NS	0	0	NS	NR	NR	NS	NR	NR	NS
Kubota et al[55]	43	62	287.3	579.3	< 0.001	2.4	21	0.004	NR	2.4	9.7	NS	0	0	NS	88.41	74.21	NS1	NR	NR	-
Montalti et al[56]	57	57	454.2	691.5	0.003	NR	NR	-	15.8	15.8	31.6	0.03	0	0	NS	60	65	NS	29	38	NS
de'Angelis et al[57]	52	52	200	300	0.001	5.8	21.2	NS	5.8	17.3	22	NS	0	3.8	NS	73.1	62.5	NS	21.1	21.1	NS
Hasegawa et al[58]	102	69	127	620	0.000	NR	NR	NR	1	8.8	24.6	0.005	0.98	1.4	NS	56.8	48.8	NS	39.7	28.6	NS

¹Data computed for 3-yr survival. LLR: Laparoscopic liver resection; OLR: Open liver resection; NR: Not reported; NS: Non significant.