Diagnosis of inflammatory bowel disease: Potential role of molecular biometrics

Figure 1 Human colon cross section depicts layers for mining proteomic patterns that delineates untreated ulcerative and Crohn’s colitis phenotype. The colon is comprised of four distinct layers: (1) the mucosa; (2) the submucosa; (3) the muscularis (two thick bands of muscle); and (4) the serosa. Comparable proteomic patterns that are mined from these layers are analyzed, based on the diagnosis [untreated ulcerative and Crohn’s colitis, (with no ambiguity)], disease activity and tissue layer.